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Yohimbe: The Definitive Guide

By Definitive Guides, Yohimbe Published on June 22, 2018 Updated on September 18, 2018
Yohimbe The Definitive Guide

If you are suffering from low libido, hormonal imbalances, or Erectile Dysfunction, the Yohimbe supplement comes to your rescue.

We know that choosing a supplement for sexual issues comes as a daunting task on its own. But, if you are looking for a herbal supplement that helps you with ED, anxiety or endurance, Yohimbe is just for you.

In this guide, you will learn what Yohimbe is, what are its benefits, recommended dosage, and a buying guide.

So, what are you waiting for?

Take heart this guide and make the most to your advantages.

What is Yohimbe?

Scientific Names: Pausinystalia Yohimbe

Yohimbe is an evergreen herb that is found in various parts of western and central Africa. Derived from the bark of an African evergreen tree, it is an alkaloid that is cultivated into the supplemental form.

Commonly used to treat Erectile Dysfunction, it has also become a growing trend among the bodybuilders to help with fat loss. (1)Riley, A. J. (1994, May-June). Yohimbine in the treatment of erectile disorder. The british Journal of Clinical Practice. 48(3):133-6. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/8031688 There are some Yohimbe supplements that consist of yohimbine as an active ingredient, while others list yohimbine hydrochloride as an active one.
Before you choose the supplement for you, learn more about the composition of the ingredient and consult your physician.

Benefits of Yohimbe

Yohimbe is used as an aphrodisiac and is being investigated for the treatment of organic impotence and diabetes.

It plays an important role in improving erections and promotes the release of nitric oxide, (2)Ajayi, A. A., Newaz, M., et al. (2003, December). Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats. Methods and Findings in Experimental and Clinical Pharmacology. 25(10):817-22. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/14735230 which leads to the dilation of blood vessels and an increase in blood flow to sexual organs.

Here is a common list of benefits observed when taking Yohimbe supplement or an extract.

Yohimbe Helps With Weight Loss

The ability of this herb to block the alpha-2 adrenergic receptors in the fat cells leads to weight loss or increased fat loss. It is also known to speed up the metabolism, improve the workout performance that helps you to lose the stubborn fat faster. This supplement comes as more effective when combined with other supplements like Synephrine and Caffeine.

Scientific Study

Boosts Endurance Levels

Yohimbe supplement improves focus, stamina, circulation during exercise. The bark of this herb supports the body’s ability to use stored fat cell for energy. Moreover, it contains alpha-2 blocking agents that trigger adrenaline and norepinephrine in the body during physical exertion.

Enhances Blood Circulation

If you are suffering from slow healing rates, cloudiness or low energy levels, the chances are that your blood circulation is not up to the optimum level. Yohimbe is a good vasodilator as it expands the blood vessels and helps improve the blood flow to provide oxygen and necessary nutrients to cells. (3)Lee, S. R., Schriefer, J. M., et al. (2013, October 21). Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acids and energy expenditure in human subjects. Lipids in Health and Disease. 12:148. doi: 10.1186/1476-511X-12-148

How Does Yohimbe Work?

Yohimbe contains a chemical compound known as yohimbine that is known to increase nerve impulses and blood flow in the sexual organs of both men and women.

It works by blocking the alpha-2 adrenergic receptors as these receptors play an important role in inhibiting the erections.

This herb promotes the release of nitric oxide that could lead the dilation of blood vessels. It is also known to counteract the sexual side effects of certain medicines that are used for stress and depression.

For weight loss, it works by increasing the adrenaline levels in the body, as well as initiating a regulatory process in fat cells that suppress the fat burning cells. Apart from this, its subset yohimbine is a fat burning compound that is primarily used to lose fat during a short-term fast. It is recommended to be taken in the fasted state because its effects are partially negated by the intake of food.

Efficacy Of Yohimbe

Yohimbe extract is a beneficial natural substance that is derived from the inner bark of the Yohimbe tree and has shown to work for various health-related issues like to dilate the blood vessels; promote sexual performance; boost in libido and stimulation of weight loss.

While the studies are still being conducted for its efficacy of Yohimbe extract, here are some case studies that show its effects on the non-organic erectile dysfunction and erectile dysfunction.

Read These Case Studies

Case Study 1

US National Library of Medicine National Institutes Of Health

Double-blind, placebo-controlled safety and efficacy trial with yohimbine hydrochloride in the treatment of nonorganic erectile dysfunction
These double-blind placebo-controlled trials of yohimbine hydrochloride had 86 patients with ED that came up without any psychological cause. (4)Vogt, H. J., Brandl, P., et al. (1997, September). Double-blind, placebo-controlled safety and efficacy trial with yohimbine hydrochloride in the treatment of nonorganic erectile dysfunction. International Journal of Impotence Research. 9(3):155-61. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/?term=Double-blind%2C+placebo-controlled+safety+and+efficacy+trial+with+yohimbine+hydrochloride+in+the+treatment+of+nonorganic+erectile+dysfunction 85 of these patients were considered for the safety, while 83 were held with the intention to treat analysis. During the research, Yohimbine was administered orally with the dosage of 30 mg per day for eight weeks. After the final evaluation of eight weeks, the patients were checked on both objective and subjective criteria. The subjective criteria included improvement in sexual satisfaction, desire, and the frequency of sexual contacts. An objective criterion was based on the penile rigidity that is determined by the use of polysomnography. After the evaluation, Yohimbe was found quite effective as a comparison to placebo. The rate of effects was 71% to 45%. There were only 7% of patients that had fair tolerance, and the experiences were mild.
Case Study 2

US National Library of Medicine National Institutes Of Health
Efficacy and Safety of Oral Combination of Yohimbine and L-arginine (SX) for the Treatment of Erectile Dysfunction
The objective of this study was to access the effectiveness and safety of SX for Erectile Dysfunction. (5)Akhondzadeh, S., Amiri, A., & Bagheri, A. H. (2010). Efficacy and Safety of Oral Combination of Yohimbine and L-arginine (SX) for the Treatment of Erectile Dysfunction: a multicenter, randomized, double blind, placebo-controlled clinical trial. Iranian Journal of Psychiatry. 5(1):1-3. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/?term=Efficacy+and+Safety+of+Oral+Combination+of+Yohimbine+and+L-arginine+(SX)+for+the+Treatment+of+Erectile+Dysfunction
It was a 4-week trial double-blind study of a group of patients with the mild to moderate ED. Forty male patients with the Erectile Dysfunction were screened for the study, who were from the age group 25-50 and had a three-month history of ED. The severity of ED was based on EF domain scores on the international index of erectile functioning. Now the patients were randomized on receiving one capsule of SX and placebo on the demand of 1:1 ratio using a code. When the results were observed after 4 weeks, just for adverse events were observed over the study.
So the study indicates that SX, i.e. a combination of Yohimbe is safe and effective for the treatment of ED, at least in the short term.

How To Take Yohimbe?

The recommended dosage for Yohimbe is 6 mg for three times a day.

Mean dosage of 0.4 mg/kg body weight or 30 mg daily and a maximum of 50 mg have been used in various erectile dysfunction studies.

For weight loss, dosages of 0.2 mg/kg body weight have been successfully used to increase the fat burning process without the adverse effects on various parameters like blood pressure and heart rate. According to this, the recommended dosage for weight loss comes as:

· 14 mg for a 150lb person
· 18 mg for a 200lb person
· 22 mg for a 250 lb person

But if you have a higher body weight than this, your cardiovascular system may not be able to handle a stimulatory agent such as Yohimbe.

Whenever you start with Yohimbe, make sure you start with a half dose and then assess the tolerance of supplement before continuing. Moreover, if you plan to pair Yohimbe with the stimulatory agents; make sure you try their half doses as the two supplements can interact negatively.

Interactions and Contraindications

You should not consume Yohimbe if you are:

· Pregnant: Yohimbe is unsafe for pregnant women as it might affect the uterus or might endanger your pregnancy. You should also not consume this supplement if you are breastfeeding.

· Suffering from PTSD: Don’t use Yohimbe if you have PTSD as it might worsen your health symptoms.

· Suffering from blood pressure issues: Consumption of small amounts of Yohimbe can increase blood pressure, while large amounts can cause low pressure.

· Surgical patient: Yohimbe simply increases the risk of bleeding. You should stop consuming Yohimbe at least two weeks before the surgery.

Side Effects

Adverse events or side effects when taking Yohimbe are usually mild. The possible side effects caused by heavy doses of Yohimbine are:

· Upset stomach
· Sleep problems
· Racing heartbeat
· Dizziness
· A headache
· Bloating
· Rashes
· Nausea and Vomits
· Sinus

The other problems cause by the heavy doses are difficulty in breathing, low blood pressure, and other heart problems.

Frequently Asked Questions

What exactly is Yohimbe?

Known as Yohimbehe and Yohimbine, it is a type of evergreen tree that is used as an aphrodisiac, a treatment for impotence, and an endurance enhancer. Moreover, it is an active compound that is found in the bark of Yohimbe that is equipped with physiological and stimulant effects.

How do I take Yohimbe?

The recommended dosage for Yohimbe is 0.2 milligrams per kilogram of body weight.

It should be taken on an empty stomach immediately after waking up or in-between the meals as it ramps up fat oxidation without causing the undesirable side effects. Furthermore, you can also consume Yohimbe an hour or two before activity.

If you have a sensitivity to the herb, take half. However, you should consult your physician if you are under any kind of medical supervision.

How does Yohimbe work?

Yohimbe along with its subset Yohimbine is the fat burning compounds, which are primarily used during short-term fasting.

It works by increasing adrenaline levels in your body, as well inhibiting the regulatory process in the fat cells that enhance the process of burning fat. Moreover, it works by blocking the alpha-2 adrenergic receptors as these receptors play an important role in inhibiting the erections.

This herb is also known to release the Nitric Oxide that could lead the dilation of blood vessels and counteracting the sexual side effects of certain medicines that are used for stress and depression.

Is Yohimbe an ED pill?

No. But the bark extract from the Yohimbe acts as a dietary supplement, which is claimed to help with erectile dysfunction (ED.

What are the benefits of Yohimbe?

The benefits of Yohimbe include-

· Treats erectile dysfunction
· Helps with weight loss
· Reduce hypertension
· Enhances endurance
· Treats dry mouth
· Boosts circulation

Can I take Yohimbe with other medications such as diabetes, cholesterol, and high blood pressure?

We cannot give you medical advice regarding your current medication and Yohimbe. If you are taking any kind of medications, we recommend consulting your doctor as some of the prescription drugs can interact with it.

Can Yohimbe help me with weight loss?

Yes. Yohimbe helps you with weight loss because it increases adrenaline levels in the blood and blocks these alpha two receptors, which increases the fat burning system. Moreover, it also increases the flow of blood to the skin’s surface and upper, lower extremities of the body.

What are the side effects of Yohimbe?

There are no side effects of Yohimbe if consumed moderately. But if you exceed its recommended consumption, the various side effects that you can face are sleep problems, dizziness, high BP, racing heartbeat, bloating, nausea, and vomits.

Is Yohimbe vegetarian safe?


For how long do I need to take Yohimbe?

If you are using Yohimbine HCL, you won’t see much of the effects if you are already quite lean. If you are looking for best results, make sure you consume it for at least 8-10 weeks.

Where is Yohimbe produced?

Yohimbe is derived from the bark of the Pausinystalia yohimbe tree in Central Africa.

It has an active chemical known as alkaloid that is found in bark and is cultivated into the supplement form.

Do I need a doctor’s prescription to take Yohimbe?

No. Yohimbe is a natural supplement so you can buy it without the doctor’s prescription. But when it comes to dosage, it is recommended to consult your doctor.

Is Yohimbe suitable for women?

Yes. The benefits of Yohimbe for women include weight loss and improvement in libido. Based on few types of research, the recommended dosage for Yohimbe is four to six grams of yohimbine HCL, three to four times a day.

Is there a chance that I won’t experience its benefits from Yohimbe?

Yes, there is a chance that you won’t experience any benefits with Yohimbe. It is just not a miracle herb, and neither has it guaranteed you to give great physiques.

If you are consuming Yohimbe, here is what you can expect from regular supplementation. The decrease in appetite, increase in energy, or an increase in metabolism.

In case, if you are not experiencing any effects, try pairing it up with the fasted routines for best results.

Is there anything that I should take apart from Yohimbe?

While Yohimbe helps you to boost your T-levels naturally, you can also do other things to boost your testosterone even more.

Yohimbe recommended for a healthy young man?

Yohimbe helps you with ED, enhances endurance, and is best to maintain your overall well-being. However, the best advantages are found in older males because who are facing ED issues or other sexual problems.

Can people with diabetes use Yohimbe?

No. the consumption of Yohimbe may cause to lower down the blood sugar by interfering with insulin or other medications that are used to control diabetes.

Do you sell Yohimbe in any other form than capsules?

Not at the moment, but you can contact us and let us know you’re interested in it.

Buying Guide

Yohimbine hydrochloride is a standardized form of Yohimbe and the active ingredient that is found in various ED drugs. If Yohimbe supplement is not labeled as natural, it is likely to be yohimbine hydrochloride.

Before you buy Yohimbe, here are some things you should know:

According to various studies, it has been found that different Yohimbe commercial supplements contain 0.1 to 489 ppm yohimbine. The supplements contain lower than stated dosage while buying the higher one could result in serious side effects.

Moreover, there have been various supplements that claim to contain botanical extract but contains man-made extract.

Due to the increasing popularity of this supplement, there are various manufacturers that use pharmaceutical grade synthetic yohimbine as an ingredient instead of the yohimbe bark extract.

To get the best of advantages of this supplement, it is important that you should purchase these supplements from CGMP compliant manufacturers to ensure that the supplement is of optimum quality.

References   [ + ]

Fran Sanchez, BSc MSc

About Fran Sanchez, BSc MSc

Fran Sanchez, founder of Herbolab, graduated from Uppsala University (Sweden) with a master in molecular biology and Karolinska University (Sweden) with a degree in medical sciences and business. He then moved to Singapore to run e-commerce operations in a pharmaceutical company, until eventually he could fulfil his dream of creating a brand dedicated to help men reach their peak performance. Drawing on his experience as a lifelong multi-sport athlete and cutting edge medical and scientific research, Fran launched herbolab tongkat ali as flagship supplement in April of 2014. Fran now spend most of his time weight lifting and creating content dedicated to improve people’s lives.

More posts by Fran Sanchez, BSc MSc

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